Soybean lecithin stabilizes disulfiram nanosuspensions with a high drug-loading content: remarkably improved antitumor efficacy

Disulfiram (DSF) has been considered as “Repurposing drug” in cancer therapy in recent years based on its good antitumor efficacy. DSF is traditionally used as an oral drug in the treatment of alcoholism. To overcome its rapid degradation and instability, DSF nanosuspensions (DSF/SPC-NSps) were prep...

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Detalhes bibliográficos
Publicado no:J Nanobiotechnology
Main Authors: Li, Haowen, Liu, Biao, Ao, Hui, Fu, Jingxin, Wang, Yian, Feng, Yue, Guo, Yifei, Wang, Xiangtao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943900/
https://ncbi.nlm.nih.gov/pubmed/31907045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-019-0565-0
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