Folate-targeting annonaceous acetogenins nanosuspensions: significantly enhanced antitumor efficacy in HeLa tumor-bearing mice

Annonaceous acetogenins (ACGs) are one of the most active constituents isolated from Annona species with potent antitumor activity. However, the poor solubility and severe side effect greatly limit their use in clinic. In this study, folic acid (FA) modified annonaceous acetogenins nanosuspensions (...

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Bibliographic Details
Published in:Drug Deliv
Main Authors: Li, Haowen, Li, Yijing, Ao, Hui, Bi, Dongdong, Han, Meihua, Guo, Yifei, Wang, Xiangtao
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058653/
https://ncbi.nlm.nih.gov/pubmed/29608108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1455761
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