Folate-targeting annonaceous acetogenins nanosuspensions: significantly enhanced antitumor efficacy in HeLa tumor-bearing mice

Annonaceous acetogenins (ACGs) are one of the most active constituents isolated from Annona species with potent antitumor activity. However, the poor solubility and severe side effect greatly limit their use in clinic. In this study, folic acid (FA) modified annonaceous acetogenins nanosuspensions (...

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Detalles Bibliográficos
Publicado en:Drug Deliv
Main Authors: Li, Haowen, Li, Yijing, Ao, Hui, Bi, Dongdong, Han, Meihua, Guo, Yifei, Wang, Xiangtao
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058653/
https://ncbi.nlm.nih.gov/pubmed/29608108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1455761
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