Folate-targeting annonaceous acetogenins nanosuspensions: significantly enhanced antitumor efficacy in HeLa tumor-bearing mice

Annonaceous acetogenins (ACGs) are one of the most active constituents isolated from Annona species with potent antitumor activity. However, the poor solubility and severe side effect greatly limit their use in clinic. In this study, folic acid (FA) modified annonaceous acetogenins nanosuspensions (...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Deliv
Hauptverfasser: Li, Haowen, Li, Yijing, Ao, Hui, Bi, Dongdong, Han, Meihua, Guo, Yifei, Wang, Xiangtao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058653/
https://ncbi.nlm.nih.gov/pubmed/29608108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1455761
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