Investigating the Binding Mode of Reversible LSD1 Inhibitors Derived from Stilbene Derivatives by 3D-QSAR, Molecular Docking, and Molecular Dynamics Simulation

Overexpression of lysine specific demethylase 1 (LSD1) has been found in many cancers. New anticancer drugs targeting LSD1 have been designed. The research on irreversible LSD1 inhibitors has entered the clinical stage, while the research on reversible LSD1 inhibitors has progressed slowly so far. I...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Molecules
Autores principales: Xu, Yongtao, He, Zihao, Yang, Min, Gao, Yunlong, Jin, Linfeng, Wang, Meiting, Zheng, Yichao, Lu, Xiaoyuan, Zhang, Songjie, Wang, Chang, Zhao, Zongya, Zhao, Junqiang, Gao, Qinghe, Duan, Yingchao
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943670/
https://ncbi.nlm.nih.gov/pubmed/31817721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24244479
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares