Regulation of cartilage damage caused by lack of Klotho with thioredoxin/peroxiredoxin (Trx/Prx) system and succedent NLRP3 activation in osteoarthritis mice

This present study aims to verify the underlying mechanism that anti-aging protein Klotho protects cartilages against the damage induced by oxidative stress. The Klotho expression level in the articular cartilages of mice with osteoarthritis (OA) was measured by using western blotting and quantitati...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Am J Transl Res
Hlavní autoři: Gu, Yanqing, Ren, Kewei, Jiang, Chunzhi, Wang, Liming, Yao, Qingqiang
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2019
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943451/
https://ncbi.nlm.nih.gov/pubmed/31934282
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky