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Regulation of cartilage damage caused by lack of Klotho with thioredoxin/peroxiredoxin (Trx/Prx) system and succedent NLRP3 activation in osteoarthritis mice

This present study aims to verify the underlying mechanism that anti-aging protein Klotho protects cartilages against the damage induced by oxidative stress. The Klotho expression level in the articular cartilages of mice with osteoarthritis (OA) was measured by using western blotting and quantitati...

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書目詳細資料
發表在:Am J Transl Res
Main Authors: Gu, Yanqing, Ren, Kewei, Jiang, Chunzhi, Wang, Liming, Yao, Qingqiang
格式: Artigo
語言:Inglês
出版: e-Century Publishing Corporation 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943451/
https://ncbi.nlm.nih.gov/pubmed/31934282
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