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Neurokinin-1 Receptor Antagonism Ameliorates Dry Eye Disease by Inhibiting Antigen-Presenting Cell Maturation and T Helper 17 Cell Activation

Neuroinflammation plays an important role in the pathogenesis of ocular surface disease, including dry eye disease (DED), but little is known about the contribution of substance P (SP) to DED. In this study, we investigated the expression of SP at the ocular surface and evaluated its effect on matur...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Yu, Man, Lee, Sang-Mok, Lee, Hyunsoo, Amouzegar, Afsaneh, Nakao, Takeshi, Chen, Yihe, Dana, Reza
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943374/
https://ncbi.nlm.nih.gov/pubmed/31669306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.09.020
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