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Restoration of Regulatory T-Cell Function in Dry Eye Disease by Antagonizing Substance P/Neurokinin-1 Receptor

Substance P (SP) is a tachykinin neuropeptide, implicated in the pathogenesis of various inflammatory conditions and a critical mediator in pain transmission. Recently, the role of SP was described in the pathogenesis of dry eye disease (DED) through its role in the maturation of antigen-presenting...

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Publicat a:Am J Pathol
Autors principals: Taketani, Yukako, Marmalidou, Anna, Dohlman, Thomas H., Singh, Rohan Bir, Amouzegar, Afsaneh, Chauhan, Sunil K., Chen, Yihe, Dana, Reza
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456741/
https://ncbi.nlm.nih.gov/pubmed/32473919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.05.011
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