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The potential role of YAP in Axl-mediated resistance to EGFR tyrosine kinase inhibitors

Yes-associated protein (YAP) is a transcription co-regulator downstream of the Hippo pathway, and plays a critical role in cancer. Although YAP regulation in the canonical Hippo pathway is well established, the Hippo-independent regulation of YAP is not well explored. Here, we showed the possible ne...

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Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Saab, Sarah, Chang, Olin Shih-Shin, Nagaoka, Kentaro, Hung, Mien-Chie, Yamaguchi, Hirohito
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943358/
https://ncbi.nlm.nih.gov/pubmed/31911857
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