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二甲双胍抑制酸性环境下的调节性T细胞增殖及功能
OBJECTIVE: To investigate the regulatory effect of metformin on regulatory T cells (Treg) in acidic environment. METHODS: CD4(+) CD25(+) Treg cells were obtained by magnetic bead sorting. Treg and conventional T cells (Tcon) cells were cultured for 24-72 h in pH 7.4 or pH 6.7 medium, and the cell pr...
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| Izdano u: | Nan Fang Yi Ke Da Xue Xue Bao |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
南方医科大学学报编辑部
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6942978/ https://ncbi.nlm.nih.gov/pubmed/31907158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2019.12.06 |
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