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二甲双胍通过调控血管平滑肌肌动蛋白骨架系统抑制小鼠动脉粥样硬化形成
OBJECTIVE: Investigate the effect and mechanism of metformin on the development of metabolic syndrome related atherosclerosis. METHOD: Transfecting EGFP-CLIP170 or EGFP-Pdlim5 plasmid to the mouse aortic smooth muscle cell line, to test the expression of p-AMPK, pCLIP-170 and pPdlim5, and observe th...
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| Publicado en: | Nan Fang Yi Ke Da Xue Xue Bao |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
南方医科大学学报编辑部
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6926088/ https://ncbi.nlm.nih.gov/pubmed/31852643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2019.11.14 |
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