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二甲双胍抑制大鼠胆管成纤维细胞胶原生成的分子信号机制
OBJECTIVE: To clarify the molecular signaling mechanism underlying the inhibitory effect of metformin on transforming growth factor-β1 (TGF-β1)-stimulated collagen I production in rat biliary fibroblasts. METHODS: Primary biliary fibroblasts were isolated under aseptic condition from 50 Sprague-Dawl...
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| Publicado no: | Nan Fang Yi Ke Da Xue Xue Bao |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
南方医科大学学报编辑部
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7277306/ https://ncbi.nlm.nih.gov/pubmed/32897197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2020.05.05 |
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