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A PI3K/AKT Scaffolding Protein, IQ motif-containing GTPase Associating Protein 1 (IQGAP1), Promotes Head and Neck Carcinogenesis

PURPOSE: Head and neck cancer (HNC) is the sixth most common cancer worldwide with a 5-year survival rate of less than 50%. The PI3K/AKT/mTOR signaling pathway is frequently implicated in HNC. Recently, IQ motif-containing GTPase activating protein 1 (IQGAP1) was discovered to scaffold the PI3K/AKT...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Wei, Tao, Choi, Suyong, Buehler, Darya, Anderson, Richard A., Lambert, Paul F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942630/
https://ncbi.nlm.nih.gov/pubmed/31597661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-1063
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