Inhibition of the Keap1-Nrf2 protein-protein interaction protects retinal cells and ameliorates retinal ischemia-reperfusion injury

The Nrf2-Keap1 pathway regulates transcription of a wide array of antioxidant and cytoprotective genes and offers critical protection against oxidative stress. This pathway has demonstrated benefit for a variety of retinal conditions. Retinal ischemia plays a pivotal role in many vision threatening...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Free Radic Biol Med
Hlavní autoři: Hui, Qiaoyan, Karlstetter, Marcus, Xu, Zhenhua, Yang, Jing, Zhou, Lingli, Eilken, Hanna M., Terjung, Carsten, Cho, Hongkwan, Gong, Junsong, Lai, Michael J., Nassar, Khaled, Duh, Elia J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942228/
https://ncbi.nlm.nih.gov/pubmed/31669760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.10.414
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky