Nrf2 has a protective role against neuronal and capillary degeneration in retinal ischemia-reperfusion injury

Retinal ischemia-reperfusion (I/R) involves extensive increase in reactive oxygen species as well as pro-inflammatory changes that result in significant histopathologic damage, including neuronal and vascular degeneration. Nrf2 has a well-known cytoprotective role in many tissues, but its protective...

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Bibliographische Detailangaben
Hauptverfasser: Wei, Yanhong, Gong, Junsong, Yoshida, Takeshi, Eberhart, Charles G., Xu, Zhenhua, Kombairaju, Ponvijay, Sporn, Michael B., Handa, James T., Duh, Elia J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997112/
https://ncbi.nlm.nih.gov/pubmed/21545836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.04.026
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