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Monomethyl fumarate promotes Nrf2-dependent neuroprotection in retinal ischemia-reperfusion

BACKGROUND: Retinal ischemia results in neuronal degeneration and contributes to the pathogenesis of multiple blinding diseases. Recently, the fumaric acid ester dimethyl fumarate (DMF) has been FDA-approved for the treatment of multiple sclerosis, based on its neuroprotective and anti-inflammatory...

詳細記述

保存先:
書誌詳細
出版年:J Neuroinflammation
主要な著者: Cho, Hongkwan, Hartsock, Matthew J., Xu, Zhenhua, He, Meihua, Duh, Elia J.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687295/
https://ncbi.nlm.nih.gov/pubmed/26689280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0452-z
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