Sharpening the Molecular Scissors: Advances in Gene-Editing Technology

The ability to precisely modify human genes has been made possible by the development of tools such as meganucleases, zinc finger nucleases, TALENs, and CRISPR/Cas. These now make it possible to generate targeted deletions, insertions, gene knock outs, and point variants; to modulate gene expression...

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Detalles Bibliográficos
Publicado en:iScience
Main Authors: Broeders, Mike, Herrero-Hernandez, Pablo, Ernst, Martijn P.T., van der Ploeg, Ans T., Pijnappel, W.W.M. Pim
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2019
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941877/
https://ncbi.nlm.nih.gov/pubmed/31901636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.100789
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