Metallochaperones Are Needed for Mycobacterium tuberculosis and Escherichia coli Nicotinamidase-Pyrazinamidase Activity

Mycobacterium tuberculosis nicotinamidase-pyrazinamidase (PZAse) is a metalloenzyme that catalyzes conversion of nicotinamide-pyrazinamide to nicotinic acid-pyrazinoic acid. This study investigated whether a metallochaperone is required for optimal PZAse activity. M. tuberculosis and Escherichia col...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Sheen, Patricia, Monsalve, Anuntxi, Campos, Jhanina, Huerta, Rodolfo, Antiparra, Ricardo, Arteaga, Héctor, Duran, Patricia, Bueno, Carlos, Kirwan, Daniela E., Gilman, Robert H., Zimic, Mirko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941528/
https://ncbi.nlm.nih.gov/pubmed/31636108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00331-19
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