Intra- and Inter-Tumor BRAF Heterogeneity in Acral Melanoma: An Immunohistochemical Analysis

The current development of BRAF inhibitors has revolutionized the treatment of unresectable melanoma. As the potential heterogeneity of BRAF mutations in melanoma has been reported, accurate detection of BRAF mutations are important. However, the genetic heterogeneity of acral melanoma—a distinct ty...

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Publicado en:Int J Mol Sci
Autores principales: Ito, Takamichi, Kaku-Ito, Yumiko, Murata, Maho, Ichiki, Toshio, Kuma, Yuki, Tanaka, Yuka, Ide, Taketoshi, Ohno, Fumitaka, Wada-Ohno, Maiko, Yamada, Yuichi, Oda, Yoshinao, Furue, Masutaka
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941107/
https://ncbi.nlm.nih.gov/pubmed/31817947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246191
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