Intra- and Inter-Tumor BRAF Heterogeneity in Acral Melanoma: An Immunohistochemical Analysis

The current development of BRAF inhibitors has revolutionized the treatment of unresectable melanoma. As the potential heterogeneity of BRAF mutations in melanoma has been reported, accurate detection of BRAF mutations are important. However, the genetic heterogeneity of acral melanoma—a distinct ty...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Ito, Takamichi, Kaku-Ito, Yumiko, Murata, Maho, Ichiki, Toshio, Kuma, Yuki, Tanaka, Yuka, Ide, Taketoshi, Ohno, Fumitaka, Wada-Ohno, Maiko, Yamada, Yuichi, Oda, Yoshinao, Furue, Masutaka
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941107/
https://ncbi.nlm.nih.gov/pubmed/31817947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246191
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