Intra- and Inter-Tumor BRAF Heterogeneity in Acral Melanoma: An Immunohistochemical Analysis

The current development of BRAF inhibitors has revolutionized the treatment of unresectable melanoma. As the potential heterogeneity of BRAF mutations in melanoma has been reported, accurate detection of BRAF mutations are important. However, the genetic heterogeneity of acral melanoma—a distinct ty...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ito, Takamichi, Kaku-Ito, Yumiko, Murata, Maho, Ichiki, Toshio, Kuma, Yuki, Tanaka, Yuka, Ide, Taketoshi, Ohno, Fumitaka, Wada-Ohno, Maiko, Yamada, Yuichi, Oda, Yoshinao, Furue, Masutaka
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941107/
https://ncbi.nlm.nih.gov/pubmed/31817947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246191
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