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Intra- and Inter-Tumor BRAF Heterogeneity in Acral Melanoma: An Immunohistochemical Analysis

The current development of BRAF inhibitors has revolutionized the treatment of unresectable melanoma. As the potential heterogeneity of BRAF mutations in melanoma has been reported, accurate detection of BRAF mutations are important. However, the genetic heterogeneity of acral melanoma—a distinct ty...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Ito, Takamichi, Kaku-Ito, Yumiko, Murata, Maho, Ichiki, Toshio, Kuma, Yuki, Tanaka, Yuka, Ide, Taketoshi, Ohno, Fumitaka, Wada-Ohno, Maiko, Yamada, Yuichi, Oda, Yoshinao, Furue, Masutaka
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941107/
https://ncbi.nlm.nih.gov/pubmed/31817947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246191
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