Hepatocyte-specific Nrf2 deficiency mitigates high-fat diet-induced hepatic steatosis: Involvement of reduced PPARγ expression

Non-alcoholic fatty liver disease (NAFLD) is an emerging global disease with increasing prevalence. However, the mechanism of NAFLD development is not fully understood. To elucidate the cell-specific role of nuclear factor erythroid-derived 2-like 2 (NRF2) in the pathogenesis of NAFLD, we utilized h...

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Vydáno v:Redox Biol
Hlavní autoři: Li, Lu, Fu, Jingqi, Liu, Dan, Sun, Jing, Hou, Yongyong, Chen, Chengjie, Shao, Junbo, Wang, Linlin, Wang, Xin, Zhao, Rui, Wang, Huihui, Andersen, Melvin E., Zhang, Qiang, Xu, Yuanyuan, Pi, Jingbo
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940621/
https://ncbi.nlm.nih.gov/pubmed/31901728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101412
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