Regulatory Role of KEAP1 and NRF2 in PPARγ Expression and Chemoresistance in Human Non-small Cell Lung Carcinoma Cells

The nuclear factor-E2-related factor 2 (NRF2) serves as a master regulator in cellular defense against oxidative stress and chemical detoxification. However, persistent activation of NRF2 resulting from mutations of NRF2 and/or downregulation or mutations of its suppressor Kelch-like ECH-associated...

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Autori principali: Zhan, Lijuan, Zhang, Hao, Zhang, Qiang, Woods, Courtney G., Chen, Yanyan, Xue, Peng, Dong, Jian, Tokar, Erik J., Xu, Yuanyuan, Hou, Yongyong, Fu, Jingqi, Yarborough, Kathy, Wang, Aiping, Qu, Weidong, Waalkes, Michael P., Andersen, Melvin E., Pi, Jingbo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418425/
https://ncbi.nlm.nih.gov/pubmed/22684020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.05.041
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