Regulatory Role of KEAP1 and NRF2 in PPARγ Expression and Chemoresistance in Human Non-small Cell Lung Carcinoma Cells

The nuclear factor-E2-related factor 2 (NRF2) serves as a master regulator in cellular defense against oxidative stress and chemical detoxification. However, persistent activation of NRF2 resulting from mutations of NRF2 and/or downregulation or mutations of its suppressor Kelch-like ECH-associated...

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Bibliografiset tiedot
Päätekijät: Zhan, Lijuan, Zhang, Hao, Zhang, Qiang, Woods, Courtney G., Chen, Yanyan, Xue, Peng, Dong, Jian, Tokar, Erik J., Xu, Yuanyuan, Hou, Yongyong, Fu, Jingqi, Yarborough, Kathy, Wang, Aiping, Qu, Weidong, Waalkes, Michael P., Andersen, Melvin E., Pi, Jingbo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418425/
https://ncbi.nlm.nih.gov/pubmed/22684020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.05.041
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