Fondaparinux pentasaccharide reduces sepsis coagulopathy and promotes survival in the baboon model of E. coli sepsis

BACKGROUND: Sepsis triggers dysfunction of coagulation and fibrinolytic systems leading to disseminated intravascular coagulation (DIC) that contributes to organ failure and death. Fondaparinux (FPX) is a synthetic pentasaccharide that binds to antithrombin (AT) and selectively inhibits factor (F) X...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Thromb Haemost
Main Authors: Keshari, Ravi S., Silasi, Robert, Popescu, Narcis I., Georgescu, Constantin, Chaaban, Hala, Lupu, Cristina, McCarty, Owen J. T., Esmon, Charles T., Lupu, Florea
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940562/
https://ncbi.nlm.nih.gov/pubmed/31549765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14642
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki