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Endocrine therapy resistance: new insights

The estrogen receptor positive (ER+) subset is the dominant contributor to global deaths from breast cancer which now exceeds 500,000 deaths annually. Lethality is driven by endocrine resistance, which has been shown to be associated with high mutational rates and extreme subclonal diversity. Treatm...

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Detalhes bibliográficos
Publicado no:Breast
Main Authors: Lei, Jonathan T., Anurag, Meenakshi, Haricharan, Svasti, Gou, Xuxu, Ellis, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939855/
https://ncbi.nlm.nih.gov/pubmed/31839155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0960-9776(19)31118-X
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