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ESR1 fusions drive endocrine therapy resistance and metastasis in breast cancer

Estrogen receptor alpha gene (ESR1) fusion transcripts have been identified in breast cancer but their role in breast cancer is not completely understood. Here, we report a causal role for ESR1 fusions in driving both endocrine therapy resistance and metastasis, and describe a therapeutic strategy t...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Cell Oncol
Päätekijät: Lei, Jonathan T., Gou, Xuxu, Ellis, Matthew J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276858/
https://ncbi.nlm.nih.gov/pubmed/30525098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1526005
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