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Therapeutic role of recurrent ESR1-CCDC170 gene fusions in breast cancer endocrine resistance

BACKGROUND: Endocrine therapy is the most common treatment for estrogen receptor (ER)-positive breast cancer, but its effectiveness is limited by high rates of primary and acquired resistance. There are likely many genetic causes, and recent studies suggest the important role of ESR1 mutations and f...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Li, Li, Lin, Ling, Veeraraghavan, Jamunarani, Hu, Yiheng, Wang, Xian, Lee, Sanghoon, Tan, Ying, Schiff, Rachel, Wang, Xiao-Song
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414578/
https://ncbi.nlm.nih.gov/pubmed/32771039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-01325-3
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