Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors

In vitro gametogenesis is the process of making germline cells from human pluripotent stem cells. The foundation of this model is the quality of the first progenitors called primordial germ cells (PGCs), which in vivo are specified during the peri-implantation window of human development. Here, we s...

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Pubblicato in:Cell Rep
Autori principali: Chen, Di, Sun, Na, Hou, Lei, Kim, Rachel, Faith, Jared, Aslanyan, Marianna, Tao, Yu, Zheng, Yi, Fu, Jianping, Liu, Wanlu, Kellis, Manolis, Clark, Amander
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939677/
https://ncbi.nlm.nih.gov/pubmed/31875561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.11.083
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