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Purkinje Cell-specific Grip1/2 Knockout Mice Show Increased Repetitive Self-Grooming and Enhanced mGluR5 Signaling in Cerebellum
Cerebellar Purkinje cell (PC) loss is a consistent pathological finding in autism. However, neural mechanisms of PC-dysfunction in autism remain poorly characterized. Glutamate receptor interacting proteins 1/2 (Grip1/2) regulate AMPA receptor (AMPAR) trafficking and synaptic strength. To evaluate r...
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| Publicado no: | Neurobiol Dis |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6939616/ https://ncbi.nlm.nih.gov/pubmed/31476380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.104602 |
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