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Histidine decarboxylase knockout mice, a genetic model of Tourette syndrome, show repetitive grooming after induced fear

Tics, such as are seen in Tourette syndrome (TS), are common and can cause profound morbidity, but they are poorly understood. Tics are potentiated by psychostimulants, stress, and sleep deprivation. Mutations in the gene histidine decarboxylase (Hdc) have been implicated as a rare genetic cause of...

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Detalhes bibliográficos
Publicado no:Neurosci Lett
Main Authors: Xu, Meiyu, Li, Lina, Ohtsu, Hiroshi, Pittenger, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424082/
https://ncbi.nlm.nih.gov/pubmed/25841792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2015.03.067
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