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Histidine decarboxylase knockout mice, a genetic model of Tourette syndrome, show repetitive grooming after induced fear

Tics, such as are seen in Tourette syndrome (TS), are common and can cause profound morbidity, but they are poorly understood. Tics are potentiated by psychostimulants, stress, and sleep deprivation. Mutations in the gene histidine decarboxylase (Hdc) have been implicated as a rare genetic cause of...

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Pubblicato in:Neurosci Lett
Autori principali: Xu, Meiyu, Li, Lina, Ohtsu, Hiroshi, Pittenger, Christopher
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424082/
https://ncbi.nlm.nih.gov/pubmed/25841792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2015.03.067
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