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Targeted Quantitative Proteomic Approach for High-Throughput Quantitative Profiling of Small GTPases in Brain Tissues of Alzheimer’s Disease Patients

Neurodegenerative disorders, including Alzheimer’s disease (AD), are prevalent among the elderly. Small GTPases of the Ras superfamily are essential regulators of intracellular trafficking and signal transduction. In this study, we develop a targeted quantification method for small GTPase proteins,...

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Библиографические подробности
Опубликовано в: :Anal Chem
Главные авторы: Huang, Ming, Darvas, Martin, Keene, C. Dirk, Wang, Yinsheng
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939614/
https://ncbi.nlm.nih.gov/pubmed/31460748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b02485
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