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Targeted Quantitative Proteomic Approach for High-Throughput Quantitative Profiling of Small GTPases in Brain Tissues of Alzheimer’s Disease Patients

Neurodegenerative disorders, including Alzheimer’s disease (AD), are prevalent among the elderly. Small GTPases of the Ras superfamily are essential regulators of intracellular trafficking and signal transduction. In this study, we develop a targeted quantification method for small GTPase proteins,...

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Bibliografische gegevens
Gepubliceerd in:Anal Chem
Hoofdauteurs: Huang, Ming, Darvas, Martin, Keene, C. Dirk, Wang, Yinsheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939614/
https://ncbi.nlm.nih.gov/pubmed/31460748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b02485
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