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A Targeted Quantitative Proteomics Strategy for Global Kinome Profiling of Cancer Cells and Tissues
Kinases are among the most intensively pursued enzyme superfamilies as targets for anti-cancer drugs. Large data sets on inhibitor potency and selectivity for more than 400 human kinases became available recently, offering the opportunity to design rationally novel kinase-based anti-cancer therapies...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Biochemistry and Molecular Biology
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977184/ https://ncbi.nlm.nih.gov/pubmed/24520089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.036905 |
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