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Roles of Small GTPases in Acquired Tamoxifen Resistance in MCF-7 Cells Revealed by Targeted, Quantitative Proteomic Analysis

Development of tamoxifen resistance remains a tremendous challenge for the treatment of estrogen-receptor (ER)-positive breast cancer. Small GTPases of the Ras superfamily play crucial roles in intracellular trafficking and cell signaling, and aberrant small-GTPase signaling is implicated in many ty...

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Udgivet i:Anal Chem
Main Authors: Huang, Ming, Wang, Yinsheng
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456261/
https://ncbi.nlm.nih.gov/pubmed/30431262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b04526
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