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Regulation of bile acid metabolism in mouse models with hydrophobic bile acid composition

The bile acid (BA) composition in mice is substantially different from that in humans. Chenodeoxycholic acid (CDCA) is an end product in the human liver; however, mouse Cyp2c70 metabolizes CDCA to hydrophilic muricholic acids (MCAs). Moreover, in humans, the gut microbiota converts the primary BAs,...

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書目詳細資料
發表在:J Lipid Res
Main Authors: Honda, Akira, Miyazaki, Teruo, Iwamoto, Junichi, Hirayama, Takeshi, Morishita, Yukio, Monma, Tadakuni, Ueda, Hajime, Mizuno, Seiya, Sugiyama, Fumihiro, Takahashi, Satoru, Ikegami, Tadashi
格式: Artigo
語言:Inglês
出版: The American Society for Biochemistry and Molecular Biology 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939601/
https://ncbi.nlm.nih.gov/pubmed/31645370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000395
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