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Regulation of bile acid metabolism in mouse models with hydrophobic bile acid composition
The bile acid (BA) composition in mice is substantially different from that in humans. Chenodeoxycholic acid (CDCA) is an end product in the human liver; however, mouse Cyp2c70 metabolizes CDCA to hydrophilic muricholic acids (MCAs). Moreover, in humans, the gut microbiota converts the primary BAs,...
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| 發表在: | J Lipid Res |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The American Society for Biochemistry and Molecular Biology
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6939601/ https://ncbi.nlm.nih.gov/pubmed/31645370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000395 |
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