High-resolution mapping of reciprocal translocation breakpoints using long-read sequencing

Long-read nanopore sequencing enables direct high-resolution breakpoint mapping on balanced carriers of reciprocal translocation. The mean sequencing depth on the translocated chromosomes to achieve accurate mapping of breakpoints ranged from 2.5-fold to 6.2-fold. To speed up determination of the br...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:MethodsX
Huvudupphovsmän: Chow, Judy F.C., Cheng, Heidi H.Y., Lau, Estella Y.L., Yeung, William S.B., Ng, Ernest H.Y.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2019
Ämnen:
Biochemistry, Genetics and Molecular Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939040/
https://ncbi.nlm.nih.gov/pubmed/31908979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mex.2019.10.028
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk