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Array comparative genomic hybridization analyses of all blastomeres of a cohort of embryos from young IVF patients revealed significant contribution of mitotic errors to embryo mosaicism at the cleavage stage

BACKGROUND: Embryos produced by in vitro fertilization (IVF) have a high level of aneuploidy, which is believed to be a major factor affecting the success of human assisted reproduction treatment. The aneuploidy rate of cleavage stage embryos based on 1–2 biopsied blastomeres has been well-reported,...

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Detalhes bibliográficos
Publicado no:Reprod Biol Endocrinol
Main Authors: Chow, Judy FC, Yeung, William SB, Lau, Estella YL, Lee, Vivian CY, Ng, Ernest HY, Ho, Pak-Chung
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256731/
https://ncbi.nlm.nih.gov/pubmed/25420429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-12-105
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