The NMDAR modulator NYX-2925 alleviates neuropathic pain via a Src-dependent mechanism in the mPFC

Previous studies have shown that oral administration of the NMDAR modulator NYX-2925 alleviates pain in several animal models of neuropathic pain and this appears to be through mPFC, but not spinal, mediated mechanisms. While much is known about the impact of neuropathic pain on NMDAR-mediated signa...

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Udgivet i:Neurobiol Pain
Main Authors: Morrison, Gladys, Asiedu, Marina N., Priebe, Jessica M., Dunning, Jacqueline, Ghoreishi-Haack, Nayereh, Kroes, Roger A., Bowers, M. Scott, Barth, Amanda L., Cearley, Cassia N., Moskal, Joseph R.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Original Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938954/
https://ncbi.nlm.nih.gov/pubmed/31909296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynpai.2019.100039
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