The NMDAR modulator NYX-2925 alleviates neuropathic pain via a Src-dependent mechanism in the mPFC

Previous studies have shown that oral administration of the NMDAR modulator NYX-2925 alleviates pain in several animal models of neuropathic pain and this appears to be through mPFC, but not spinal, mediated mechanisms. While much is known about the impact of neuropathic pain on NMDAR-mediated signa...

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Detalhes bibliográficos
Publicado no:Neurobiol Pain
Main Authors: Morrison, Gladys, Asiedu, Marina N., Priebe, Jessica M., Dunning, Jacqueline, Ghoreishi-Haack, Nayereh, Kroes, Roger A., Bowers, M. Scott, Barth, Amanda L., Cearley, Cassia N., Moskal, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938954/
https://ncbi.nlm.nih.gov/pubmed/31909296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynpai.2019.100039
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