Hypoxia promotes pulmonary vascular remodeling via HIF-1α to regulate mitochondrial dynamics

BACKGROUND: Increasing research suggests that mitochondrial defect plays a major role in pulmonary hypertension (PH) pathogenesis. Mitochondrial dynamics and quality control have a central role in the maintenance of the cell proliferation and apoptosis balance. However, the molecular mechanism under...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Geriatr Cardiol
Main Authors: Chen, Xi, Yao, Jia-Mei, Fang, Xia, Zhang, Cui, Yang, Yu-Shu, Hu, Cheng-Ping, Chen, Qiong, Zhong, Guang-Wei
Format: Artigo
Jezik:Inglês
Izdano: Science Press 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938735/
https://ncbi.nlm.nih.gov/pubmed/31911790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.11909/j.issn.1671-5411.2019.12.003
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