Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia

Mitochondria fulfill vital metabolic functions and act as crucial cellular signaling hubs, integrating their metabolic status into the cellular context. Here, we show that defective cardiolipin remodeling, upon loss of the cardiolipin acyl transferase tafazzin, decreases HIF-1α signaling in hypoxia....

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Chowdhury, Arpita, Aich, Abhishek, Jain, Gaurav, Wozny, Katharina, Lüchtenborg, Christian, Hartmann, Magnus, Bernhard, Olaf, Balleiniger, Martina, Alfar, Ezzaldin Ahmed, Zieseniss, Anke, Toischer, Karl, Guan, Kaomei, Rizzoli, Silvio O., Brügger, Britta, Fischer, Andrè, Katschinski, Dörthe M., Rehling, Peter, Dudek, Jan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205837/
https://ncbi.nlm.nih.gov/pubmed/30332638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.09.057
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