Hypoxia Modulates Fibroblastic Architecture, Adhesion and Migration: A Role for HIF-1α in Cofilin Regulation and Cytoplasmic Actin Distribution

Cells can adapt to hypoxia by various mechanisms. Yet, hypoxia-induced effects on the cytoskeleton-based cell architecture and functions are largely unknown. Here we present a comprehensive analysis of the architecture and function of L929 fibroblasts under hypoxic conditions (1% O(2)). Cells cultiv...

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Détails bibliographiques
Auteurs principaux: Vogler, Melanie, Vogel, Sabine, Krull, Sabine, Farhat, Katja, Leisering, Pia, Lutz, Susanne, Wuertz, Christina M., Katschinski, Dörthe M., Zieseniss, Anke
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715466/
https://ncbi.nlm.nih.gov/pubmed/23874890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069128
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