Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia

Mitochondria fulfill vital metabolic functions and act as crucial cellular signaling hubs, integrating their metabolic status into the cellular context. Here, we show that defective cardiolipin remodeling, upon loss of the cardiolipin acyl transferase tafazzin, decreases HIF-1α signaling in hypoxia....

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cell Rep
Main Authors: Chowdhury, Arpita, Aich, Abhishek, Jain, Gaurav, Wozny, Katharina, Lüchtenborg, Christian, Hartmann, Magnus, Bernhard, Olaf, Balleiniger, Martina, Alfar, Ezzaldin Ahmed, Zieseniss, Anke, Toischer, Karl, Guan, Kaomei, Rizzoli, Silvio O., Brügger, Britta, Fischer, Andrè, Katschinski, Dörthe M., Rehling, Peter, Dudek, Jan
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2018
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205837/
https://ncbi.nlm.nih.gov/pubmed/30332638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.09.057
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares