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Exploring the Trans-Cleavage Activity of CRISPR Cas12a (cpf1) for the Development of a Universal Electrochemical Biosensor

An accurate, rapid, and cost-effective biosensing strategy for the quantification of disease biomarkers is vital for the development of early-diagnostic point-of-care systems, benefiting overall human health. The recent discovery of the trans-cleavage activity of CRISPR type V effectors makes CRISPR...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Dai, Yifan, Somoza, Rodrigo A, Wang, Liu, Welter, Jean F, Li, Yan, Caplan, Arnold I, Liu, Chung Chiun
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938695/
https://ncbi.nlm.nih.gov/pubmed/31568601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201910772
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