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Detecting, categorizing, and correcting coverage anomalies of RNA-seq quantification

Due to incomplete reference transcriptomes, incomplete sequencing bias models, or other modeling defects, algorithms to infer isoform expression from RNA-seq sometimes do not accurately model expression. We present a computational method to detect instances where a quantification algorithm could not...

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Publicat a:Cell Syst
Autors principals: Ma, Cong, Kingsford, Carl
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938679/
https://ncbi.nlm.nih.gov/pubmed/31786209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.10.005
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