Induction of AP-1 by YAP/TAZ contributes to cell proliferation and organ growth

Yes-associated protein (YAP) and its homolog transcriptional coactivator with PDZ-binding motif (TAZ) are key effectors of the Hippo pathway to control cell growth and organ size, of which dysregulation yields to tumorigenesis or hypertrophy. Upon activation, YAP/TAZ translocate into the nucleus and...

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Vydáno v:Genes Dev
Hlavní autoři: Koo, Ja Hyun, Plouffe, Steven W., Meng, Zhipeng, Lee, Da-Hye, Yang, Di, Lim, Dae-Sik, Wang, Cun-Yu, Guan, Kun-Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938666/
https://ncbi.nlm.nih.gov/pubmed/31831627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.331546.119
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