Short- and medium-term impact of bariatric surgery on the activities of CYP2D6, CYP3A4, CYP2C9, and CYP1A2 in morbid obesity

Morbid obesity and bariatric surgery induce anatomical, physiological and metabolic alterations that may alter the body’s disposition of drugs. Current literature on this topic is limited and sometimes inconsistent. Cytochrome P450 (CYP) is a superfamily of enzymes that metabolize around 75% of all...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Rodríguez-Morató, Jose, Goday, Albert, Langohr, Klaus, Pujadas, Mitona, Civit, Ester, Pérez-Mañá, Clara, Papaseit, Esther, Ramon, Jose Manuel, Benaiges, David, Castañer, Olga, Farré, Magí, de la Torre, Rafael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938522/
https://ncbi.nlm.nih.gov/pubmed/31892725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57002-9
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