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MDMA, methamphetamine, and CYP2D6 pharmacogenetics: what is clinically relevant?
In vitro human studies show that the metabolism of most amphetamine-like psychostimulants is regulated by the polymorphic cytochrome P450 isozyme CYP2D6. Two compounds, methamphetamine and 3,4-methylenedioxymethamphetamine (MDMA), were selected as archetypes to discuss the translation and clinical s...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3495276/ https://ncbi.nlm.nih.gov/pubmed/23162568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00235 |
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