Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”): The Influence of Gender and Genetics (CYP2D6, COMT, 5-HTT)

The synthetic psychostimulant MDMA (±3,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). It has been suggested that women are more sensitive to MDMA effects than men b...

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Detalhes bibliográficos
Main Authors: Pardo-Lozano, Ricardo, Farré, Magí, Yubero-Lahoz, Samanta, O’Mathúna, Brian, Torrens, Marta, Mustata, Cristina, Pérez-Mañá, Clara, Langohr, Klaus, Cuyàs, Elisabet, Carbó, Marcel·lí, de la Torre, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480420/
https://ncbi.nlm.nih.gov/pubmed/23112822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047599
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